CBDV, or cannabidivarin, is one of many molecules derived from
cannabis and hemp plants. These molecules, commonly referred to as
cannabinoids, are partially responsible for the many effects and
therapeutic benefits cannabis has to offer. CBDV is structurally
similar to CBD (cannabidiol). Like CBD, CBDV is not intoxicating
when isolated, so it won’t cause the euphoric high associated with
high-THC cannabis.
Much of the research around CBDV has centered around its effect on
seizures. GW Pharmaceuticals, which developed the first
FDA-approved CBD drug called Epidiolex, is actively developing a
CBDV-based drug known as GPW42006 to reduce or prevent epileptic
and other forms of seizures. Their research has shown that CBDV
affects the neurochemical pathway of the capsaicin receptors
involved in both the onset as well as the progression of several
types of epilepsy. GW reports that CBDV has shown anti-epileptic
results “across a range of in vitro and in vivo models of
epilepsy.
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